BDBM50153588 CHEMBL3775480::US10053456, 119::US10414761, Example 84::US10968213, Example 119::US9487511, 84::US9718814, 84::US9920047, 119

SMILES Cc1nnc(NC(=O)c2cc(cs2)[C@@H]2C[C@H]2NC2CCC2)s1

InChI Key InChIKey=ALKUEFQXLXYBPP-NWDGAFQWSA-N

Data  97 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50153588   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-A: The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-A: The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-A: The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-A: The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-A: The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50153588(CHEMBL3775480 | US10053456, 119 | US10414761, Exam...)
Affinity DataIC50: >1.00E+5nMAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In DepthDetails US Patent